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PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated

カタログ番号 TMPK-00662
別名: PDCD1LG1, B7-H1, B7H1, CD274, B7-H, PDCD1L1, PD-L1B7 homolog 1, PDL1, PD-L1

B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26 kDa and the accession number is G7PSE7.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 187,000
500 μg 約5 days ¥ 746,000
1 mg 約5 days ¥ 1,248,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance. PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26 kDa and the accession number is G7PSE7.
Species Cynomolgus,Rhesus
Expression Host HEK293 Cells
Tag C-His
Accession Number G7PSE7
別名 PDCD1LG1, B7-H1, B7H1, CD274, B7-H, PDCD1L1, PD-L1B7 homolog 1, PDL1, PD-L1
Construction Phe19-Arg238
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 The protein has a predicted MW of 26 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background B7-H1, also known as PD-L1 and CD274, is an approximately 65 kDa transmembrane glycoprotein in the B7 family of immune regulatory molecules. PD-L1 has been identified as the ligand for the immunoinhibitory receptor programmed death-1(PD1/PDCD1) and has been demonstrated to play a role in the regulation of immune responses and peripheral tolerance.

参考文献

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Keywords

PD-L1 Protein (Primary Amine Labeling), Cynomolgus/Rhesus macaque, Recombinant (His), Biotinylated PDL-1 PDCD1LG1 CD 274 B7-H1 B7H1 CD274 B7-H PDCD1L1 PD-L1B7 homolog 1 PDL1 PDL 1 CD-274 PD-L1 recombinant recombinant-proteins proteins protein