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ALK Protein, Mouse, Recombinant (hFc)

カタログ番号 TMPK-00927
別名: CD246, Anaplastic lymphoma kinase, ALK tyrosine kinase receptor

Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
ALK Protein, Mouse, Recombinant (hFc)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 90,500
500 μg 約5 days ¥ 360,500
1 mg 約5 days ¥ 606,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises.
Species Mouse
Expression Host HEK293 Cells
Tag C-hFc
Accession Number P97793
別名 CD246, Anaplastic lymphoma kinase, ALK tyrosine kinase receptor
Construction Ser19-Cys692
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 101.11 kDa (predicted). Due to glycosylation, the protein migrates to 115-125 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in PBS, 10% Glycerol (pH 7.4).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Anaplastic lymphoma kinase (ALK) is mostly known for its oncogenic role in several human cancers. Recent evidences clearly indicate new roles of ALK and its genetic aberrations (e.g. gene rearrangements and mutations) in immune evasion, innate and cell-mediated immunity. New ALK-related immunotherapy approaches are demonstrating both preclinical and clinical promises.

参考文献

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

ALK Protein, Mouse, Recombinant (hFc) CD 246 CD246 CD-246 Anaplastic lymphoma kinase ALK tyrosine kinase receptor recombinant recombinant-proteins proteins protein