APLN Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages.

APLN Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 187,000
500 μg	約5 days	￥ 746,000
1 mg	約5 days	￥ 1,248,500

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説明	Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages.

Species	Mouse
Expression Host	HEK293 Cells
Tag	C-hFc-Avi
Accession Number	Q9R0R4
別名	APEL, APJ endogenous ligand, Apelin
Construction	Val23-Phe77
Protein Purity	> 95% as determined by Tris-Bis PAGE
分子量	34.81 kDa (predicted). Due to enzyme lysis and glycosylation, the protein migrates to 38-48 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 0.2M Arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Macrophages play key roles during cardiovascular diseases (CVD) and their related complications.Apelin (APLN) is a key molecule, whose roles during CVD have been documented previously. Therefore, it has been hypothesized that APLN may perform its roles via modulation of macrophages.

参考文献

1. Arababadi MK, et al. APLN/APJ pathway: The key regulator of macrophage functions. Life Sci. 2019 Sep 1;232:116645. doi: 10.1016/j.lfs.2019.116645. Epub 2019 Jul 10. PMID: 31299236.

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APLN Protein, Mouse, Recombinant (hFc & Avi), Biotinylated

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