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Apolipoprotein M/APOM Protein, Human, Recombinant (hFc)

カタログ番号 TMPY-02716
別名: apolipoprotein M, NG20, DADB-127H9.5, HSPC336, apo-M, G3a

Apolipoprotein M/APOM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.6 kDa and the accession number is O95445.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Apolipoprotein M/APOM Protein, Human, Recombinant (hFc)
パッケージサイズ 在庫状況 単価(税別)
50 μg 在庫あり ¥ 73,500
100 μg 約5 days ¥ 125,500
200 μg 約5 days ¥ 214,500
500 μg 約5 days ¥ 434,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
生物学的情報 Testing in progress
説明 Apolipoprotein M/APOM Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 45.6 kDa and the accession number is O95445.
Species Human
Expression Host HEK293 Cells
Tag C-hFc
Accession Number O95445
別名 apolipoprotein M, NG20, DADB-127H9.5, HSPC336, apo-M, G3a
Construction The Human APOM (O95445) (Met 1-Asn 188) was fused with the Fc region of Human IgG1 at the C-terminus.
Protein Purity > 85 % as determined by SDS-PAGE

分子量 45.6 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background ApoM (apolipoprotein M) is an apolipoprotein and member of the lipocalin protein family. The lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They have an eight-stranded, antiparallel, symmetrical _-barrel fold, which is in essence a beta sheet which has been rolled into a cylindrical shape. Inside this barrel is located a ligand binding site. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. Lipocalins have been associated with many biological processes, among them immune response, pheromone transport, biological prostaglandin synthesis, retinoid binding, and cancer cell interactions. Lipocalins are comparatively small in size, and are thus less complicated to study as opposed to large, bulky proteins. They can also bind to various ligands for different biological purposes. ApoM is associated with high density lipoproteins and to a lesser extent with low density lipoproteins and triglyceride-rich lipoproteins. ApoM is involved in lipid transport and can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.

参考文献

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Keywords

Apolipoprotein M/APOM Protein, Human, Recombinant (hFc) apolipoprotein M HSPC-336 NG 20 HSPC 336 NG-20 NG20 DADB-127H9.5 HSPC336 apo-M G3a recombinant recombinant-proteins proteins protein