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B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled

カタログ番号 TMPK-01016
別名: B7H3,  UNQ309, PRO352, PSEC0249, B7 homolog 3, B7-H3, CD276

B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 321,500
500 μg 約5 days ¥ 854,000
1 mg 約5 days ¥ 1,425,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 50.1 kDa and the accession number is Q5ZPR3-2.
Species Human
Expression Host HEK293 Cells
Tag C-hFc
Accession Number Q5ZPR3-2
別名 B7H3,  UNQ309, PRO352, PSEC0249, B7 homolog 3, B7-H3, CD276
Construction Leu29-Pro245
Protein Purity > 95% as determined by Tris-Bis PAGE
分子量 The protein has a predicted MW of 50.1 kDa. Due to glycosylation, the protein migrates to 65-70 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.

参考文献

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Keywords

B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled B7H3  UNQ309 UNQ309 PRO352 PSEC 0249 PSEC0249 CD-276 B7 homolog 3 UNQ 309 PRO-352 UNQ-309 PSEC-0249 CD 276 B7-H3 CD276 PRO 352 recombinant recombinant-proteins proteins protein