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BDNF Protein, Rat, Recombinant (His)

カタログ番号 TMPH-03251
別名: Brain-derived neurotrophic factor, BDNF

BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
BDNF Protein, Rat, Recombinant (His)
パッケージサイズ 在庫状況 単価(税別)
20 μg 約20 days ¥ 65,500
100 μg 約20 days ¥ 123,500
1 mg 約20 days ¥ 528,000
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生物学的特性に関する説明
Technical Params
Product Properties
説明 BDNF Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession number is P23363.
Species Rat
Expression Host E. coli
Tag N-6xHis
Accession Number P23363
別名 Brain-derived neurotrophic factor, BDNF
Amino Acid RRGELSVCDSISEWVTAADKKTAVDMSGGTVTVLEKVPVSKGQLKQYFYETKCNPMGYTKEGCRGIDKRHWNSQCRTTQSYVRALTMDSKKRIGWRFIRIDTSCVCTL
Construction 136-243 aa
Protein Purity > 90% as determined by SDS-PAGE.
分子量 16.3 kDa (predicted)
Formulation Tris-based buffer, 50% glycerol
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Important signaling molecule that activates signaling cascades downstream of NTRK2. During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.; Important signaling molecule that activates signaling cascades downstream of NTRK2. Activates signaling cascades via the heterodimeric receptor formed by NGFR and SORCS2. Signaling via NGFR and SORCS2 plays a role in synaptic plasticity and long-term depression (LTD). Binding to NGFR and SORCS2 promotes neuronal apoptosis. Promotes neuronal growth cone collapse.

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技術サポート

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

BDNF Protein, Rat, Recombinant (His) Brain-derived neurotrophic factor BDNF recombinant recombinant-proteins proteins protein