BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is C8C060.

BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

パッケージサイズ	在庫状況	単価(税別)
20 μg	約5 days	￥ 63,500
100 μg	約5 days	￥ 124,000
1 mg	約5 days	￥ 808,000

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説明	BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13 kDa and the accession number is C8C060.

Species	Human,Mouse,Rat,Rhesus,Canine
Expression Host	E. coli
Tag	Tag Free
Accession Number	C8C060
別名	bone morphogenetic protein 2
Construction	The mature form of Human / Mouse / Rat / rhesus / canine BMP2 (NP_001191.1) (Gln283-Arg396) was expressed with an initial Met. The mature form sequences of Human, Mouse, Rat, rhesus and canine BMP2 are identical.
Protein Purity	> 95 % as determined by SDS-PAGE
分子量	13 kDa (predicted)

Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 3% CAN, 1% TFA. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

参考文献

1. Jiao X, et al. (2007) Heparan sulfate proteoglycans (HSPGs) modulate BMP-2 osteogenic bioactivity in C2C12 cells. J Biol Chem. 282(2):1080-6. 2. Michon F, et al. (2008) BMP-2 and BMP-7 play antagonistic roles in feather induction. Development 135 (16):2797-805.

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BMP-2 Protein, Human, Mouse, Rat, Rhesus, Canine, Recombinant

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