CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 76.17 kDa and the accession number is Q8WXI7.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 112,000 |
500 μg | 約5 days | ¥ 447,500 |
1 mg | 約5 days | ¥ 746,000 |
説明 | CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 76.17 kDa and the accession number is Q8WXI7. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-His |
Accession Number | Q8WXI7 |
別名 | CA125, MUC16, CA125MUC-16, FLJ14303, CA-125 |
Construction | Asp12783-Ser13467 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 76.17 kDa (predicted). Due to glycosylation, the protein migrates to 90-140 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | MUC16, also known as the CA125 antigen, is a mucin protein that may be found in type I transmembrane or secreted forms that are used monitor the progress of epithelial ovarian cancer therapy.Thought to provide a protective, lubricating barrier against particles and infectious agents at mucosal surfaces.Binding to MSLN mediates heterotypic cell adhesion. This may contribute to the metastasis of ovarian cancer to the peritoneum by initiating cell attachment to the mesothelial epithelium via binding to MSLN. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His) CA125 MUC16 CA125MUC-16 FLJ14303 FLJ 14303 MUC 16 CA-125 FLJ-14303 MUC-16 CA 125 recombinant recombinant-proteins proteins protein