CCL20 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.1 kDa and the accession number is O89093-1.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
20 μg | 約5 days | ¥ 49,000 |
100 μg | 約5 days | ¥ 124,000 |
1 mg | 約5 days | ¥ 808,000 |
説明 | CCL20 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.1 kDa and the accession number is O89093-1. |
Species | Mouse |
Expression Host | E. coli |
Tag | Tag Free |
Accession Number | O89093-1 |
別名 | LARC, MIP-3A, Scya20, chemokine (C-C motif) ligand 20, exodus-1, MIP-3[a], MIP3A, ST38, CKb4 |
Construction | The Mouse CCL20 (NP_058656.1) (Ala28-Met97) was expressed with an initial Met. |
Protein Purity | > 95 % as determined by SDS-PAGE. |
分子量 | 8.1 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CCL20 Protein, Mouse, Recombinant LARC MIP-3A Scya20 chemokine (C-C motif) ligand 20 exodus-1 MIP-3[a] MIP3A ST38 ST-38 CKb4 ST 38 recombinant recombinant-proteins proteins protein