CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is Q08722.
説明 | CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Fc-Avi tag. The predicted molecular weight is 60-70 KDa and the accession number is Q08722. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-hFc-Avi |
Accession Number | Q08722 |
別名 | Protein MER6, MER6, IAP, CD47, Antigenic surface determinant protein OA3, Integrin-associated protein, Leukocyte surface antigen CD47 |
Amino Acid | Gln19-Pro139 |
Construction | Gln19-Pro139 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 60-70 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | CD47(Integrin-Associated Protein,IAP) is a 40 ‑ 60 kDa variably glycosylated atypical member of the immunoglobulin superfamily. The ubiquitously expressed CD47 binds to SIRP family members on macrophages, neutrophils, and T cells. CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CD47 Protein, Human, Recombinant (hFc & Avi), Biotinylated CD-47 Protein MER6 MER 6 MER6 IAP CD47 Antigenic surface determinant protein OA3 MER-6 Integrin-associated protein Leukocyte surface antigen CD47 CD 47 recombinant recombinant-proteins proteins protein