CD81 Protein, Human, Recombinant

CD81 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 9.9 kDa and the accession number is A0A024RCB7.

CD81 Protein, Human, Recombinant

パッケージサイズ	在庫状況	単価(税別)
100 μg	在庫あり	￥ 88,500
200 μg	約5 days	￥ 151,500
500 μg	約5 days	￥ 307,500

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生物学的情報	Testing in progress
説明	CD81 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 9.9 kDa and the accession number is A0A024RCB7.

Species	Human
Expression Host	HEK293 Cells
Tag	Tag Free
Accession Number	A0A024RCB7
別名	S5.7, CVID6, TSPAN28, TAPA1, CD81 molecule
Construction	The Human CD81 (NP_004347.1) (Phe113-Lys201) was expressed with two additional amino acids (Gly&Pro) at the N-terminus.
Protein Purity	> 90 % as determined by SDS-PAGE
分子量	9.9 kDa (predicted)

Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.

参考文献

1. Petracca R. et al., 2000, J Virol. 74 (10): 4824-30. 2. Bartosch B. et al., 2003, The Journal of Biological Chemistry. 278 (43): 41624-30. 3. Clark KL. et al., 2001, Journal of Immunology. 167 (9): 5115-21.

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CD81 Protein, Human, Recombinant

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