CD81 Protein, Human, Recombinant (His)

CD81 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.1 kDa and the accession number is A0A024RCB7.

CD81 Protein, Human, Recombinant (His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 161,000
1 mg	約5 days	￥ 1,049,000

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説明	CD81 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 12.1 kDa and the accession number is A0A024RCB7.

Species	Human
Expression Host	HEK293 Cells
Tag	N-His
Accession Number	A0A024RCB7
別名	TSPAN28, TAPA1, CVID6, S5.7, CD81 molecule
Construction	Human CD81 (NP_004347.1) (Phe113-Lys201)
Protein Purity	> 90 % as determined by SDS-PAGE.
分子量	12.1 kDa (predicted)

Endotoxin	< 1.0 EU/μg of the protein as determined by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition.

参考文献

1. Petracca R. et al., 2000, J Virol. 74 (10): 4824-30. 2. Bartosch B. et al., 2003, The Journal of Biological Chemistry. 278 (43): 41624-30. 3. Clark KL. et al., 2001, Journal of Immunology. 167 (9): 5115-21.

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CD81 Protein, Human, Recombinant (His)

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