CDH11 Protein, Human, Recombinant (aa 54-617, His)

CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis.

CDH11 Protein, Human, Recombinant (aa 54-617, His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 112,000
500 μg	約5 days	￥ 447,500
1 mg	約5 days	￥ 746,000

バルクのお問い合わせ

説明

Species	Human
Expression Host	HEK293 Cells
Tag	C-His
Accession Number	AAA35622
別名	CDH11, Osteoblast cadherin, OSF-4, CAD11OSF-4, OB, Cadherin-11, OB-cadherin, CDHOB
Construction	Gly54-Thr617
Protein Purity	> 90% as determined by Tris-Bis PAGE
分子量	66.32 kDa (predicted). Due to glycosylation, the protein migrates to 67-70 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	CDH11 belongs to a group of transmembrane proteins that are principally located in adherens junctions. CDH11 mediates homophilic cell-to-cell adhesion, which may promote the development of cirrhosis. CDH11 expression was positively correlated with liver fibrosis in patients with cirrhosis, and could therefore be a prognostic factor in patients with liver fibrosis.

参考文献

1. Ruan W, et al. CDH11 promotes liver fibrosis via activation of hepatic stellate cells. Biochem Biophys Res Commun. 2019 Jan 8;508(2):543-549. doi: 10.1016/j.bbrc.2018.11.153. Epub 2018 Nov 30. PMID: 30509494.

Calculator

Reconstitution Calculator

Recombinant Proteins Dilute Calculator

Specific Activity Calculator

bottom

CDH11 Protein, Human, Recombinant (aa 54-617, His)

参考文献

Calculator

技術サポート

Keywords