CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
20 μg | 約20 days | ¥ 65,500 |
100 μg | 約20 days | ¥ 123,500 |
1 mg | 約20 days | ¥ 528,000 |
説明 | CDK5R1 Protein, Human, Recombinant (His) is expressed in E. coli. |
Species | Human |
Expression Host | E. coli |
Tag | N-6xHis |
Accession Number | Q15078 |
別名 | CDK5 activator 1, CDK5R, NCK5A, CDK5R1, Cyclin-dependent kinase 5 activator 1, TPKII regulatory subunit, Cyclin-dependent kinase 5 regulatory subunit 1 |
Amino Acid | AQPPPAQPPAPPASQLSGSQTGGSSSVKKAPHPAVTSAGTPKRVIVQASTSELLRCLGEFLCRRCYRLKHLSPTDPVLWLRSVDRSLLLQGWQDQGFITPANVVFLYMLCRDVISSEVGSDHELQAVLLTCLYLSYSYMGNEISYPLKPFLVESCKEAFWDRCLSVINLMSSKMLQINADPHYFTQVFSDLKNESGQEDKKRLLLGLDR |
Construction | 99-307 aa |
Protein Purity | > 85% as determined by SDS-PAGE. |
分子量 | 27.3 kDa (predicted) |
Formulation | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | p35 is a neuron specific activator of CDK5. The complex p35/CDK5 is required for neurite outgrowth and cortical lamination. Involved in dendritic spine morphogenesis by mediating the EFNA1-EPHA4 signaling. Activator of TPKII. The complex p35/CDK5 participates in the regulation of the circadian clock by modulating the function of CLOCK protein: phosphorylates CLOCK at 'Thr-451' and 'Thr-461' and regulates the transcriptional activity of the CLOCK-ARNTL/BMAL1 heterodimer in association with altered stability and subcellular distribution. |
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Please read the User Guide of Recombinant Proteins for more specific information.
CDK5R1 Protein, Human, Recombinant (His) CDK5 activator 1 CDK5R NCK5A CDK5R1 Cyclin-dependent kinase 5 activator 1 TPKII regulatory subunit Cyclin-dependent kinase 5 regulatory subunit 1 recombinant recombinant-proteins proteins protein