Claudin-18.1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-8xHis tag. The predicted molecular weight is 18 KDa and the accession number is P56856.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 71,500 |
50 μg | 約5 days | ¥ 153,500 |
500 μg | 約5 days | ¥ 626,500 |
1 mg | 約5 days | ¥ 1,003,000 |
説明 | Claudin-18.1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-8xHis tag. The predicted molecular weight is 18 KDa and the accession number is P56856. |
Species | Human |
Expression Host | E. coli |
Tag | N-8xHis |
Accession Number | P56856 |
別名 | CLDN18, Claudin-18 |
Amino Acid | Asp28-Leu76 |
Construction | Asp28-Leu76 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 18 KDa (reducing condition) |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 8% Sucrose, 2% Glycine, 20% Glycerol, 5 mM DTT, 0.05% Tween 80, pH 8.0. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Claudin-18(CLDN18) is a protein that in humans is encoded by the CLDN18 gene. It belongs to the group of claudins. CLDN18 belongs to the large claudin family of proteins, which form tight junction strands in epithelial cells. CLDN18 plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity. CLDN18 has two isoform A1 and isoform A2. IMAB362 (Claudiximab) is a monoclonal antibody against isoform 2 of Claudin-18. It is under investigation for the treatment of gastrointestinal adenocarcinomas and pancreatic tumors. IMAB362 was developed by Ganymed Pharmaceuticals AG. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Claudin-18.1 Protein, Human, Recombinant (His) CLDN18 CLDN 18 CLDN-18 Claudin-18 recombinant recombinant-proteins proteins protein