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Coagulation factor XI Protein, Cynomolgus, Recombinant (His)

カタログ番号 TMPK-01271
別名: F11, PTA, FXI, Coagulation factor XI

Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).

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Coagulation factor XI Protein, Cynomolgus, Recombinant (His)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 112,000
500 μg 約5 days ¥ 447,500
1 mg 約5 days ¥ 746,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).
Species Cynomolgus
Expression Host HEK293 Cells
Tag C-His
Accession Number XP_005556540.2
別名 F11, PTA, FXI, Coagulation factor XI
Construction Glu44-Ala650
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 69.05 kDa (predicted). Due to glycosylation, the protein migrates to 70-85 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Factor XI (FXI) is the zymogen of a plasma protease (FXIa) that contributes to hemostasis by activating factor IX (FIX). In the original cascade model of coagulation, FXI is converted to FXIa by factor XIIa (FXIIa), a component, along with prekallikrein and high-molecular-weight kininogen (HK), of the plasma kallikrein-kinin system (KKS).

参考文献

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

Coagulation factor XI Protein, Cynomolgus, Recombinant (His) F11 PTA FXI F 11 Coagulation factor XI F-11 recombinant recombinant-proteins proteins protein