Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted
helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one
TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many
tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by
PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I
collagen; it may serve to maintain the integrity of the extracellular matrix.
| 説明 |
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted
helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one
TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many
tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by
PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I
collagen; it may serve to maintain the integrity of the extracellular matrix. |
| Species |
Human
|
| Expression Host |
HEK293 Cells
|
| Tag |
C-6xHis
|
| Accession Number |
Q96P44
|
| 別名 |
collagen, type XXI, alpha 1, COL21A1, FLJ44623, DKFZp564B052, collagen alpha-1(XXI) chain, collagen, type XXI, α1, MGC26619, dJ682J15.1, COLA1L, α 1 type XXI collagen, dJ708F5.1, FLJ39125, collagen α-1(XXI) chain, FP633, alpha 1 type XXI collagen
|
| Amino Acid |
Glu23-Tyr957
|
| Construction |
Glu23-Tyr957
|
| Protein Purity |
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
|
| 分子量 |
115-125&220 KDa (reducing condition)
|
| Endotoxin |
< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
|
| Formulation |
Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
|
| Reconstitution |
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
|
| Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
|
| Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.
|
| Research Background |
Collagen α-1(XXI) Chain (COL21A1) is a member of the fibril-associated collagens with interrupted
helices (FACIT) family. COL21A1 is a secreted protein and contains six collagen-like domains, one
TSP N-terminal (TSPN) domain, and one VWFA domain. COL21A1 is widely expressed in many
tissues with the highest expression observed at the fetal stage. COL21A1 is stimulated by
PDGF/platelet-derived growth factor. Type XXI collagen is localized to tissues containing type I
collagen; it may serve to maintain the integrity of the extracellular matrix.
|
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