Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 122,500 |
500 μg | 約5 days | ¥ 491,500 |
1 mg | 約5 days | ¥ 819,500 |
説明 | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 52.2 kDa and the accession number is P03953-1. |
Species | Mouse |
Expression Host | HEK293 Cells |
Tag | C-hFc |
Accession Number | P03953-1 |
別名 | C3 convertase activator, AMBP-1, PFD, FACTOR D, CFD, ADN, EC 3.4.21.46, Complement factor D, DF, EC 3.4.21, Adipsin |
Construction | Ile26-Ser259 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC |
分子量 | 52.2 kDa (predicted). Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in 20 mM Tris, 500 mM NaCl (pH 7.4). |
Stability & Storage |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. |
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Complement Factor D/CFD Protein, Mouse, Recombinant (hFc) C3 convertase activator AMBP-1 PFD AMBP1 FACTOR D AMBP 1 CFD ADN EC 3.4.21.46 Complement factor D DF EC 3.4.21 Adipsin recombinant recombinant-proteins proteins protein