CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated

Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma.

CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 187,000
500 μg	約5 days	￥ 746,000
1 mg	約5 days	￥ 1,248,500

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説明

Species	Mouse
Expression Host	HEK293 Cells
Tag	C-His-Avi
Accession Number	O35188
別名	Neurotactin, CXC3C, ABCD-3, Fkn, Fractalkine, NTT, Cx3cl1, SCYD1, Cx3c, C3Xkine, CXC3, NTN
Construction	Gln25-Thr336
Protein Purity	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量	36 kDa (predicted). Due to glycosylation, the protein migrates to 70-83 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Fractalkine/CX3C chemokine ligand 1 (CX3CL1) is a chemokine involved in the anticancer function of lymphocytes-mainly NK cells, T cells and dendritic cells. Its increased levels in tumors improve the prognosis for cancer patients, although it is also associated with a poorer prognosis in some types of cancers, such as pancreatic ductal adenocarcinoma.

参考文献

1. Korbecki J, et al. Fractalkine/CX3CL1 in Neoplastic Processes. Int J Mol Sci. 2020 May 25;21(10):3723. doi: 10.3390/ijms21103723. PMID: 32466280; PMCID: PMC7279446.

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CX3CL1/Fractalkine Protein, Mouse, Recombinant (His & Avi), Biotinylated

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