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CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)

カタログ番号 TMPK-00018
別名: BLC, SCYB13, ANGIE, ANGIE2, BCA-1, BLR1L, BCA1

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) is expressed in E. coli expression system with N-His-Sumo tag. The predicted molecular weight is 22.9 kDa and the accession number is O43927.

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CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 107,000
500 μg 約5 days ¥ 424,500
1 mg 約5 days ¥ 711,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) is expressed in E. coli expression system with N-His-Sumo tag. The predicted molecular weight is 22.9 kDa and the accession number is O43927.
Species Human
Expression Host E. coli
Tag N-His-Sumo
Accession Number O43927
別名 BLC, SCYB13, ANGIE, ANGIE2, BCA-1, BLR1L, BCA1
Construction Val23-Pro109
Protein Purity > 95% as determined by Tris-Bis PAGE
分子量 22.9 kDa (predicted). The protein migrates to 26-28 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in 0.1M Glycine, 0.3M NaCl, 0.2M L-arginine, 10% Glycerol (pH 3.0).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

参考文献

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Keywords

CXCL13/BCA-1 Protein, Human, Recombinant (His & Sumo) BLC ANGIE 2 SCYB13 SCYB-13 ANGIE SCYB 13 ANGIE-2 ANGIE2 BCA-1 BLR1L BCA 1 BCA1 recombinant recombinant-proteins proteins protein