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CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)

カタログ番号 TMPK-00734
別名: ANGIE, ANGIE2, BCA-1, BLR1L, BLC, BCA1, SCYB13

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.1 kDa and the accession number is O55038.

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CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc)
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 107,000
500 μg 約5 days ¥ 424,500
1 mg 約5 days ¥ 711,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice. CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with N-hFc tag. The predicted molecular weight is 37.1 kDa and the accession number is O55038.
Species Mouse
Expression Host HEK293 Cells
Tag N-hFc
Accession Number O55038
別名 ANGIE, ANGIE2, BCA-1, BLR1L, BLC, BCA1, SCYB13
Construction Ile22-Ala109
Protein Purity > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
分子量 37.1 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in 50 mM Tris, 500 mM NaCl (pH 7.5).
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

参考文献

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Keywords

CXCL13/BCA-1 Protein, Mouse, Recombinant (hFc) ANGIE SCYB-13 ANGIE2 BCA-1 BLR1L BLC BCA1 BCA 1 SCYB13 SCYB 13 ANGIE 2 ANGIE-2 recombinant recombinant-proteins proteins protein