Ephrin A1/EFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.08 kDa and the accession number is P20827-1.
生物学的情報 |
Immobilized Ephrin-A1 Protein, Human, Recombinant (hFc Tag) at 2 μg/mL (100 μL/well) can bind EphA2 Protein, Mouse, Recombinant (His Tag), the EC50 is 13-64 ng/mL.
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説明 | Ephrin A1/EFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.08 kDa and the accession number is P20827-1. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-hFc |
Accession Number | P20827-1 |
別名 | EPLG1, TNFAIP4, ECKLG, LERK-1, LERK1, EFL1, EFNA1, B61, ephrin-A1 |
Construction | The Human EFNA1 (NP_004419.2) (Met1-Ser182) was expressed with the Fc region of Human IgG1 at the C-terminus. |
Protein Purity |
> 95 % as determined by SDS-PAGE.
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分子量 | 46.08 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | EPH-related receptor tyrosine kinase ligand 1 (abbreviated as Ephrin-A1) also known as ligand of eph-related kinase 1 or EFNA1, is a member of the ephrin (EPH) family. The Eph family receptor interacting proteins (ephrins) are a family of proteins that serve as the ligands of the Eph receptor, which compose the largest known subfamily of receptor protein-tyrosine kinases (RTKs). Ephrin-A1/EFNA1 and its Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins. Ephrin-A1 and one of its receptor EphA2 were expressed in xenograft endothelial cells and also tumor cells and play a role in human cancers, at least in part by influencing tumor neovascularization. |
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Please read the User Guide of Recombinant Proteins for more specific information.
Ephrin A1/EFNA1 Protein, Human, Recombinant (hFc) EPLG1 TNFAIP4 EFNA-1 TNFAIP-4 ECKLG TNFAIP 4 EFL 1 LERK-1 B 61 LERK1 LERK 1 B-61 EFL1 EFNA 1 EFNA1 EPLG 1 EPLG-1 B61 ephrin-A1 EFL-1 recombinant recombinant-proteins proteins protein