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Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)

カタログ番号 TMPY-06714
別名: coagulation factor IX

Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.17 kDa and the accession number is A0A8J8XCV8.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His)
パッケージサイズ 在庫状況 単価(税別)
50 μg 約5 days ¥ 138,000
500 μg 約5 days ¥ 897,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.17 kDa and the accession number is A0A8J8XCV8.
Species Cynomolgus
Expression Host HEK293 Cells
Tag C-His
Accession Number A0A8J8XCV8
別名 coagulation factor IX
Construction The Cynomolgus F9 (A0A8J8XCV8) (Met1-Thr461) was expressed with a polyhistidine tag at the C-terminus.
Protein Purity ≥ 95 % as determined by SDS-PAGE. ≥ 95 % as determined by SEC-HPLC.
分子量 50.17 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background Coagulation factor IX, also known as Christmas factor, Plasma thromboplastin component and PTC, is a secreted protein which belongs to the peptidase S1 family. Coagulation factor IX / F9 contains two EGF-like domains, one Gla (gamma-carboxy-glutamate) domain and one?peptidase S1 domain. Coagulation factor IX / F9 is a vitamin K-dependent plasma protein that participates in the intrinsic pathway of blood coagulation by converting factor X to its active form in the presence of Ca2+ons, phospholipids, and factor VIIIa. Defects in Coagulation factor IX / F9 are the cause of thrombophilia due to factor IX defect which is a hemostatic disorder characterized by a tendency to thrombosis. Defects in Coagulation factor IX / F9 are also the cause of recessive X-linked hemophilia B ( HEMB ) which also known as Christmas disease.

参考文献

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Keywords

Coagulation factor IX/F9 Protein, Cynomolgus, Recombinant (His) coagulation factor IX recombinant recombinant-proteins proteins protein