Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia).
説明 | Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia). |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-His |
Accession Number | Q96LA5-1 |
別名 | IFGP4, FCRH2, CD307b, SPAP1, SPAP1B, Fc receptor like 2, SPAP1C, FCRL2, SPAP1A, IRTA4 |
Construction | The Human FCRL2 (NP_110391.2) (Met1-Asp395) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity | > 90 % as determined by SDS-PAGE. |
分子量 | 42.5 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in CLL (B-cell chronic lymphocytic leukemia). |
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Please read the User Guide of Recombinant Proteins for more specific information.
FcRH2/FCRL2 Protein, Human, Recombinant (His) IFGP4 FCRH2 IFGP-4 FCRL-2 IFGP 4 SPAP-1 CD307b SPAP1 FCRH-2 SPAP 1 IRTA-4 SPAP1B Fc receptor like 2 IRTA 4 SPAP1C FCRH 2 FCRL 2 FCRL2 SPAP1A IRTA4 recombinant recombinant-proteins proteins protein