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FGF-14 Protein, Human, Recombinant (isoform 1B)

カタログ番号 TMPY-02804
別名: SCA27, FHF-4, FGF-14, fibroblast growth factor 14, FHF4

FGF-14 Protein, Human, Recombinant (isoform 1B) is expressed in E. coli expression system. The predicted molecular weight is 21.1kDa and the accession number is Q92915-2.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
FGF-14 Protein, Human, Recombinant (isoform 1B)
パッケージサイズ 在庫状況 単価(税別)
50 μg 約5 days ¥ 106,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 FGF-14 Protein, Human, Recombinant (isoform 1B) is expressed in E. coli expression system. The predicted molecular weight is 21.1kDa and the accession number is Q92915-2.
Species Human
Expression Host E. coli
Tag Tag Free
Accession Number Q92915-2
別名 SCA27, FHF-4, FGF-14, fibroblast growth factor 14, FHF4
Construction The Human FGF14 isoform 1B (NP_787125.1) (Lys 64-Thr 252) was expressed and purified.
Protein Purity > 97 % as determined by SDS-PAGE
分子量 21.1kDa (predicted)
Endotoxin Please contact us for more information.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.5. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice.

Research Background FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF14 is probably involved in nervous system development and function. Defects in FGF14 are the cause of spinocerebellar ataxia type 27 (SCA27). It is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA27 is an autosomal dominant cerebellar ataxia. It is a slowly progressive disorder, with onset in late-childhood to early adulthood, characterized by ataxia with tremor, orofacial dyskinesia, psychiatric symptoms and cognitive deficits.

参考文献

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

FGF-14 Protein, Human, Recombinant (isoform 1B) SCA-27 FGF 14 SCA27 FHF-4 FGF-14 SCA 27 fibroblast growth factor 14 FHF 4 FHF4 FGF14 recombinant recombinant-proteins proteins protein