FKBP25/FKBP3 Protein, Human, Recombinant (GST)

FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation during NSCLC development.

FKBP25/FKBP3 Protein, Human, Recombinant (GST)

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 161,000

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説明	FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation during NSCLC development.

Species	Human
Expression Host	E. coli
Tag	GST
Accession Number	Q00688
別名	FKBP-25, PPIase, FKBP25, FK506 binding protein 3, FKBP-3
Construction	The Human FKBP3 (Q00688) (Ala 2-Asp 224) was fused with the GST tag at the N-terminus.
Protein Purity	> 90 % as determined by SDS-PAGE
分子量	52 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM tris, 0.15M NaCl, 0.5 mM GSH, pH 8.0.Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	FKBP3 is a member of FK506-binding proteins (FKBPs). miR-145-5p overexpression suppressed cell proliferation of NSCLC cells which was abrogated by FKBP3 overexpression, that FKBP3/Sp1/HDAC2/p27 control cell proliferation during NSCLC development.

参考文献

1. Wiederrecht G., et al., 1992, Biochem. Biophys. Res. Commun. 185: 298 - 303. 2. Dephoure N., et al.,2008, Proc. Natl. Acad. Sci. USA.105:10762-7. 3. Gauci S., et al., 2009, Anal. Chem. 81:4493-4501. 4. Choudhary C., et al., 2009, Science. 325:834-840.

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FKBP25/FKBP3 Protein, Human, Recombinant (GST)

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