Galectin-3 Protein, Mouse, Recombinant (His)

Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion.

Galectin-3 Protein, Mouse, Recombinant (His)

パッケージサイズ	在庫状況	単価(税別)
100 μg	在庫あり	￥ 62,000
500 μg	約5 days	￥ 245,500
1 mg	約5 days	￥ 643,000

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生物学的情報	Mouse Galectin-3, His Tag immobilized on CM5 Chip can bind Mouse LGALS3BP, His Tag with an affinity constant of 17.56 nM as determined in SPR assay.
説明	Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion.

Species	Mouse
Expression Host	HEK293 Cells
Tag	C-His
Accession Number	P16110
別名	Galectin3, LGALS2, AGE-R3, L31, LGALS3, Mac-2, GAL3, L29, Gal-3, GALIG, MAC2GAL3, Lectin L-29, GALBPCBP35, CBP35, galactin-3
Construction	Ala2-Ile264
Protein Purity	> 95% as determined by Tris-Bis PAGE
分子量	28.5 kDa (predicted). Due to glycosylation, the protein migrates to 43-50 kDa based on Tris-Bis PAGE result.

Endotoxin	< 1 EU/μg by the LAL method.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, 300 mM L-arginine (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
Reconstitution	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	Galectin-3 (Gal-3) is a 30 kDa β-galactose, highly conserved and widely distributed intracellularly and extracellularly. Gal-3 has been demonstrated in recent years to be a novel inflammatory factor participating in the process of intravascular inflammation, lipid endocytosis, macrophage activation, cellular proliferation, monocyte chemotaxis, and cell adhesion.

参考文献

1. Gao L, et al. Role of APLP2 in the prognosis and clinicopathology of renal cell carcinoma. Oncol Lett. 2019 Jan;17(1):508-513. doi: 10.3892/ol.2018.9577. Epub 2018 Oct 15. PMID: 30655794; PMCID: PMC6313182.

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Galectin-3 Protein, Mouse, Recombinant (His)

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