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GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)

カタログ番号 TMPJ-00356
別名: GHBP, GHR, Somatotropin receptor, growth hormone receptor, growth hormone binding protein, GH receptor, serum binding protein

Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc)
パッケージサイズ 在庫状況 単価(税別)
10 μg 約5 days ¥ 21,000
50 μg 約5 days ¥ 51,000
500 μg 約5 days ¥ 360,500
1 mg 約5 days ¥ 512,000
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生物学的特性に関する説明
Technical Params
Product Properties
説明 Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.
Species Mouse
Expression Host HEK293 Cells
Tag C-hFc
Accession Number Q3UP14
別名 GHBP, GHR, Somatotropin receptor, growth hormone receptor, growth hormone binding protein, GH receptor, serum binding protein
Amino Acid Met1-Gln273
Construction Met1-Gln273
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 65-90 KDa (reducing condition)
Endotoxin < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesized and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.

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技術サポート

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

GHR/Growth Hormone R Protein, Mouse, Recombinant (hFc) GHBP GHR Somatotropin receptor growth hormone receptor growth hormone binding protein GH receptor serum binding protein recombinant recombinant-proteins proteins protein