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GPRC5D Protein-VLP, Cynomolgus, Recombinant

カタログ番号 TMPK-00528
別名: MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor

Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.10 kDa and the accession number is A0A2K5W6I7.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
GPRC5D Protein-VLP, Cynomolgus, Recombinant
パッケージサイズ 在庫状況 単価(税別)
100 μg 約5 days ¥ 372,000
500 μg 約5 days ¥ 1,496,500
1 mg 約5 days ¥ 2,495,000
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA. GPRC5D Protein-VLP, Cynomolgus, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 35.10 kDa and the accession number is A0A2K5W6I7.
Species Cynomolgus
Expression Host HEK293 Cells
Accession Number A0A2K5W6I7
別名 MGC129713, GPRC5D, MGC129714, orphan G-protein coupled receptor
Construction Met1-Cys300
Protein Purity > 95% as determined by HPLC
分子量 The target protein has a predicted MW of 35.10 kDa.
Endotoxin < 1 EU/μg by the LAL method.
Formulation Supplied as 0.22 μm filtered solution in PBS (pH 7.4).Notice: If you need it for immunization, Do Not use any adjuvant.
Stability & Storage

It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.

参考文献

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Keywords

GPRC5D Protein-VLP, Cynomolgus, Recombinant MGC129713 MGC-129713 MGC 129714 MGC-129714 GPRC5D MGC129714 MGC 129713 orphan G-protein coupled receptor recombinant recombinant-proteins proteins protein