ホーム 計算ツール
代理店ログイン

Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated

カタログ番号 TMPY-05571
別名: CD33 molecule, Siglec-3, p67, SIGLEC3

Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated is expressed in HEK293 mammalian cells. The accession number is AAH28152.1.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated
パッケージサイズ 在庫状況 単価(税別)
25 μg 約5 days ¥ 88,500
100 μg 約5 days ¥ 213,500
ご確認事項

1. 1研究室・グループあたり最大5製品までお申し込みいただけます。 同一製品は1回のみとなります。

2. 1回につき最大2製品までのお申し込みが可能です。

3. 2回目以降をご希望の際は、前回ご提供のサンプルの実験結果をオンラインでご提供いただく必要がございます。

4. 2023 年 1 月 20 日より前にサンプルをお申し込みいただいたお客様は、2023 年の無料申請枠にはカウントされませんが、以前の実験結果をご提供いただく必要があります。

Get quote
Contact us for more batch information
生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated is expressed in HEK293 mammalian cells. The accession number is AAH28152.1.
Species Human
Expression Host HEK293 Cells
Tag Tag Free
Accession Number AAH28152.1
別名 CD33 molecule, Siglec-3, p67, SIGLEC3
Construction Recombinant Human CD33 (AAH28152.1, Met1-His259) are conjugated with FITC under optimum conditions, the unreacted FITC was removed.
Formulation Aqueous solution containing 0.5% BSA and 0.03% Proclin 300
Stability & Storage

This reagent is stable for 6 months when stored at 2℃ - 8℃. Protected from prolonged exposure to light. Do not freeze !

Shipping

Shipping with blue ice.

Research Background Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This Single-pass type I membrane protein contains 1 Ig-like C2-type (immunoglobulin-like) domain and 1 Ig-like V-type (immunoglobulin-like) domain. CD33 /Siglec-3 is a putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. CD33 /Siglec-3 preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. CD33/Siglec-3 induces apoptosis in acute myeloid leukemia (in vitro). CD33/Siglec-3 can function as a sialic acid-dependent cell adhesion molecule and that binding can be modulated by endogenous sialoglycoconjugates when CD33 is expressed in a plasma membrane.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

参考文献

Calculator

Reconstitution Calculator
Recombinant Proteins Dilute Calculator
Specific Activity Calculator
=
÷
X
=
X
(Unit/mg)
= 106 ÷
ng/mL

bottom

技術サポート

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

Siglec-3/CD33 Protein, Human, Recombinant, FITC conjugated CD33 molecule Siglec-3 p67 SIGLEC3 SIGLEC 3 recombinant recombinant-proteins proteins protein