CD38 Protein, Human, Recombinant (His), PE conjugated

CD38 Protein, Human, Recombinant (His), PE conjugated is expressed in HEK293 mammalian cells with His tag. The accession number is NP_001766.2.

CD38 Protein, Human, Recombinant (His), PE conjugated

生物学的情報	Tested by Flow cytometric analysis of anti-CD38 CAR expression.
説明	CD38 Protein, Human, Recombinant (His), PE conjugated is expressed in HEK293 mammalian cells with His tag. The accession number is NP_001766.2.

Species	Human
Expression Host	HEK293
Tag	His
Accession Number	NP_001766.2
別名	T10, ADPRC1, ADPRC 1, CD38 molecule
Construction	Recombinant human CD38 (NP_001766.2, extracellular domain, Val 43-Ile 300) are conjugated with PE under optimum conditions, the unreacted PE was removed.

Formulation	Aqueous solution containing 0. 5% BSA and 0. 03%Proclin 300
Stability & Storage	This reagent is stable for 6 months from date of receipt when stored at 2℃ - 8℃. Protected from prolonged exposure to light. Do not freeze !
Shipping	Shipping at ambient temperature.
Research Background	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. Cluster of differentiation 38 (CD38), also known as ADP-ribosyl cyclase, is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B and natural killer cells. It shares several characteristics with ADP-ribosyl cyclase 2 CD157. CD38 is a multifunctional ectoenzyme that catalyzes the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+to ADP-ribose. It also functions in cell adhesion, signal transduction and calcium signaling. CD38 has been used as a prognostic marker in leukemia. It can also be used to identify plasma cells.

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