IL-11 Protein, Cynomolgus, Recombinant

IL-11 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.39 kDa and the accession number is P20808.

IL-11 Protein, Cynomolgus, Recombinant

パッケージサイズ	在庫状況	単価(税別)
10 μg	在庫あり	￥ 31,500
20 μg	約5 days	￥ 46,500
50 μg	約5 days	￥ 79,500
100 μg	約5 days	￥ 136,000
200 μg	約5 days	￥ 232,000
500 μg	約5 days	￥ 468,500

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生物学的情報	Testing in progress
説明	IL-11 Protein, Cynomolgus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 19.39 kDa and the accession number is P20808.

Species	Cynomolgus
Expression Host	E. coli
Tag	Tag Free
Accession Number	P20808
別名	interleukin 11
Construction	cynomolgus IL11 (XP_005595839.2) (Phe22-Leu199)
Protein Purity	> 90 % as determined by SDS-PAGE.
分子量	19.39 kDa (predicted)

Endotoxin	Please contact us for more information.
Formulation	Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM Tris, 50 mM NaCl, pH 8.3. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization.
Reconstitution	A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
Shipping	In general, Lyophilized powders are shipping with blue ice.
Research Background	IL11 is a multifunctional cytokine first isolated in 199 from bone marrow-derived stromal cells. It is a key regulator of multiple events in hematopoiesis, most notably the stimulation of megakaryocyte maturation. IL11 is also known under the names adipogenesis inhibitory factor (AGIF) and oprelvekin. IL11 can improve platelet recovery after chemotherapy-induced thrombocytopenia, induce acute-phase proteins, modulate antigen-antibody responses, participate in the regulation of bone cell proliferation and differentiation, and could be used as a therapeutic for osteoporosis. IL11 stimulates the growth of certain lymphocytes and, in the murine model, stimulates an increase in the cortical thickness and strength of long bones. As a signaling molecule, IL11 has a variety of functions associated with its receptor interleukin 11 receptor alpha; such functions include placentation and to some extent of decidualization.

参考文献

1. McKinley D. et al., 1992, Genomics. 13 (3): 814-9. 2. Paul SR. et al., 1990, Proc Natl Acad Sci. 87 (19): 7512-6. 3. Kawashima I. et al., 1991, FEBS Lett. 283 (2): 199-202.

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IL-11 Protein, Cynomolgus, Recombinant

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