IL-13 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is AAK53823.1.
パッケージサイズ | 在庫状況 | 単価(税別) |
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50 μg | 在庫あり | ¥ 68,000 |
100 μg | 約5 days | ¥ 120,500 |
200 μg | 約5 days | ¥ 212,000 |
500 μg | 約5 days | ¥ 447,500 |
生物学的情報 |
Measured by its binding ability in a functional ELISA. Immobilized recombinant human IL13RA2 at 8 μg/ml (100 μl/well) can bind IL13 with a linear range of 0.25-8.0 ng/ml.
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説明 | IL-13 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39 kDa and the accession number is AAK53823.1. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | hFc |
Accession Number | AAK53823.1 |
別名 | IL-13, ALRH, interleukin 13, P600 |
Construction | The mature form of Human IL13 (AAK53823.1) (Gly 21-Asn 132) was fused with the Fc region of Human IgG1 at the N-terminus. |
Protein Purity |
> 98 % as determined by SDS-PAGE
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分子量 | 39 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Interleukin 13 (IL-13) is a single-chain glycosylated polypeptide, which belongs to the IL-13/IL-4 family. IL-13 protein is secreted by many cell types, but especially by T helper type 2 (Th2) cells. IL-13 exerts its effects through a multi-subunit receptor comprising the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains (IL-13 Rα1 and IL-13 Rα2). As a cytokine, IL-13 protein is critical in regulating inflammatory, immune responses, and diseases. Also, it inhibits the production of pro-inflammatory cytokines and chemokines, and thus down-regulates macrophage activity. IL-13 protein and antibody are more importantly implicated as a central mediator of immunoregulatory processes in various cell types.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-13 Protein, Human, Recombinant (hFc) P-600 IL-13 ALRH IL 13 P 600 interleukin 13 IL13 P600 recombinant recombinant-proteins proteins protein