IL-13 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 38-60 KDa and the accession number is AAK53823.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 35,500 |
50 μg | 約5 days | ¥ 107,000 |
500 μg | 約5 days | ¥ 636,000 |
1 mg | 約5 days | ¥ 952,500 |
生物学的情報 | Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells The ED50 for this effect is 300 ng/ml. (Regularly tested); |
説明 | IL-13 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 38-60 KDa and the accession number is AAK53823. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-mFc |
Accession Number | AAK53823 |
別名 | Interleukin-13, IL-13 |
Amino Acid | Gly21Asn132 |
Construction | Gly21Asn132 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 38-60 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-13 Protein, Human, Recombinant (mFc) Interleukin-13 IL-13 IL13 IL 13 recombinant recombinant-proteins proteins protein