IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-70 KDa and the accession number is Q9NPH3-2.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 11,000 |
50 μg | 約5 days | ¥ 34,000 |
500 μg | 約5 days | ¥ 219,500 |
1 mg | 約5 days | ¥ 314,500 |
説明 | IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 50-70 KDa and the accession number is Q9NPH3-2. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-6xHis |
Accession Number | Q9NPH3-2 |
別名 | IL1RAP, Interleukin-1 Receptor Accessory Protein, IL-1R-3, C3orf13, Interleukin-1 Receptor 3, IL1R3, IL-1RAcP, IL-1 Receptor Accessory Protein, IL-1R3 |
Amino Acid | Ser21-Gln356 |
Construction | Ser21-Gln356 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 50-70 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.2. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Interleukin-1 Receptor Accessory Protein (IL-1RAcP) is a member of the interleukin-1 receptor family. It contains three Ig-like C2-type domains in the extracellular region and a long cytoplasmic domain implicated in signal transduction. IL-1RAcP acts as a non-ligand binding accessory component of the receptors for IL1α, IL1βand IL33. IL-1RAcP mediates interleukin-1-dependent activation of NF-kappa-B. It is part of the membrane-bound form of the IL-1 receptor. IL-1 RAcP takes part in the Signaling ways by the formation of a ternary complex containing IL1R1, TOLLIP, MYD88, and IRAK1 or IRAK2. In addition, IL-1RAcP modulates the response to interleukins by associating with soluble IL1R1 and enhancing interleukin-binding to the decoy receptor. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (aa 21-356, His) IL1RAP Interleukin-1 Receptor Accessory Protein IL-1R-3 C3orf13 Interleukin-1 Receptor 3 IL1R3 IL-1RAcP IL-1 Receptor Accessory Protein IL-1R3 recombinant recombinant-proteins proteins protein