IL-20 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NYY1.
パッケージサイズ | 在庫状況 | 単価(税別) |
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20 μg | 在庫あり | ¥ 41,000 |
100 μg | 約5 days | ¥ 102,500 |
200 μg | 約5 days | ¥ 181,000 |
生物学的情報 |
Measured in a cell proliferation assay using BaF3 mouse pro-B cells transfected with human IL20 Rα and human IL20 Rβ. The ED50 for this effect is typically 0.25-2.5 ng/mL.
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説明 | IL-20 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.7 kDa and the accession number is Q9NYY1. |
Species | Human |
Expression Host | E. coli |
Tag | Tag Free |
Accession Number | Q9NYY1 |
別名 | ZCYTO10, interleukin-20, IL10D, interleukin 20, IL-20 |
Construction | The mature form of Human IL20 (Q9NYY1) (Leu25-Glu176) was expressed, with a N-terminal Met. |
Protein Purity |
> 95 % as determined by SDS-PAGE
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分子量 | 17.7 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | IL20/Interleukin-20 belongs to the IL-10 family. It is a cytokine structurally related to interleukin 10. IL20/Interleukin-20 can be detected in skin, trachea, and other tissues. It is produced by activated keratinocytes and monocytes and transmits an intracellular signal through two distinct cell-surface receptor complexes on keratinocytes and other epithelial cells. It has been shown that interleukin-20 transduces its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. It may be involved in epidermal function and psoriasis. It also regulates the proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. Also, IL20/Interleukin-20 also causes cell expansion of multipotential hematopoietic progenitor cells. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-20 Protein, Human, Recombinant ZCYTO-10 IL20 IL 20 ZCYTO10 interleukin-20 IL10D ZCYTO 10 interleukin 20 IL-20 recombinant recombinant-proteins proteins protein