The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 187,000 |
500 μg | 約5 days | ¥ 746,000 |
1 mg | 約5 days | ¥ 1,248,500 |
説明 | The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma. |
Species | Mouse |
Expression Host | HEK293 Cells |
Tag | C-His-Avi |
Accession Number | Q9EQ14 |
別名 | Interleukin-23 subunit α, Interleukin-23 subunit alpha, IL-23 subunit alpha, IL-23 subunit α, IL-23p19, P19, IL23A, SGRF, IL-23-A, Interleukin-23 subunit p19, IL23p19 |
Construction | Val22-Ala196 |
Protein Purity | > 95% as determined by Tris-Bis PAGE; > 90% as determined by HPLC |
分子量 | 22.60 kDa (predicted). Due to glycosylation, the protein migrates to 25-30 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | The heterodimeric cytokine interleukin-23 (IL-23 or IL23A/IL12B) is produced by dendritic cells and macrophages and promotes the proinflammatory and regenerative activities of T helper 17 (Th17) and innate lymphoid cells. A recent study has reported that IL-23 is also secreted by lung adenoma cells and generates an inflammatory and immune-suppressed stroma. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
IL-23 P19/IL23A Protein, Mouse, Recombinant (His & Avi), Biotinylated Interleukin-23 subunit α Interleukin-23 subunit alpha P 19 IL-23 subunit alpha P-19 IL-23 subunit α IL-23p19 P19 IL23A SGRF IL-23-A Interleukin-23 subunit p19 IL23p19 recombinant recombinant-proteins proteins protein