IL-34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q8R1R4-1.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
50 μg | 在庫あり | ¥ 41,000 |
100 μg | 約5 days | ¥ 71,500 |
200 μg | 約5 days | ¥ 126,500 |
500 μg | 約5 days | ¥ 266,500 |
生物学的情報 |
1. Measured by its ability to bind biotinylated recombinant mouse CSF1R in a functional ELISA.
2. Measured in a cell proliferation assay using M-NFS-60 mouse myeloid cells. The ED50 for this effect is typically 50-200 ng/mL.
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説明 | IL-34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q8R1R4-1. |
Species | Mouse |
Expression Host | HEK293 Cells |
Tag | C-His |
Accession Number | Q8R1R4-1 |
別名 | interleukin 34, 2010004A03Rik, AI593503 |
Construction | The extracellular domain (Met 1-Pro 235) of Mouse mIL34 (NP_001128572.1) precursor was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity |
> 90 % as determined by SDS-PAGE
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分子量 | 26 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | IL34 (Interleukin 34) is a Protein Coding gene. IL-34, also known as uncharacterized protein C16 or f77 homolog, belongs to the IL-34 family. IL-34 is a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R). IL-34 protein is expressed in various tissues, including heart, brain, lung, liver, kidney, spleen, thymus, testes, ovary, small intestine, prostate, and colon, and most abundant in the spleen. The colony-stimulating factor 1 receptor (CSF-1R) is identified as the receptor for IL-34. IL-34 increases the growth or survival of immune cells known as monocytes. Besides, IL-34 promoted the formation of the colony-forming unit-macrophage (CFU-M), a macrophage progenitor, in human bone marrow cultures. |
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Please read the User Guide of Recombinant Proteins for more specific information.
IL-34 Protein, Mouse, Recombinant (His) AI-593503 interleukin 34 2010004A03Rik AI 593503 AI593503 recombinant recombinant-proteins proteins protein