JAM-B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-39 KDa and the accession number is P57087.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 19,500 |
50 μg | 約5 days | ¥ 59,500 |
500 μg | 約5 days | ¥ 436,000 |
1 mg | 約5 days | ¥ 626,500 |
説明 | JAM-B Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 35-39 KDa and the accession number is P57087. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-6xHis |
Accession Number | P57087 |
別名 | C21orf43, VE-JAM, Junctional Adhesion Molecule 2, VEJAM, JAM-2, Junctional Adhesion Molecule B, JAM2, CD322, JAM-B, Vascular Endothelial Junction-Associated Molecule |
Amino Acid | Phe29-Asn236 |
Construction | Phe29-Asn236 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 35-39 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris-HCl, 150 mM NaCl, pH 8.0. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. |
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Please read the User Guide of Recombinant Proteins for more specific information.
JAM-B Protein, Human, Recombinant (His) C21orf43 VE-JAM CD-322 Junctional Adhesion Molecule 2 VEJAM JAM-2 Junctional Adhesion Molecule B JAM2 CD 322 CD322 JAM-B JAM 2 Vascular Endothelial Junction-Associated Molecule recombinant recombinant-proteins proteins protein