KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 在庫あり | ¥ 103,500 |
200 μg | 約5 days | ¥ 183,500 |
500 μg | 約5 days | ¥ 388,000 |
生物学的情報 | Testing in progress |
説明 | KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-His |
Accession Number | Q8N743 |
別名 | KIR44, KIR3DL7, CD158Z, KIRC1, killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3, KIR2DS2 |
Construction | The Human KIR3DL3 (NP_703144.2) (Met1-Leu322) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity |
> 95 % as determined by SDS-PAGE
|
分子量 | 33.7 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | KIR3DL3 (Killer Cell Immunoglobulin Like Receptor, Three Ig Domains And Long Cytoplasmic Tail 3) is a Protein Coding gene. KIR3DL3 is a framework gene of the Leukocyte Receptor Complex, present in all individuals and haplotypes analyzed to date.KIR3DL3 alleles were characterized by two families and one unrelated individual. The most centromeric gene in the human KIR cluster is KIR3DL3. The encoded protein belongs to the immunoglobulin superfamily. KIR3DL3 has only one immunoreceptor tyrosine-based inhibitory motif and lacks the exon encoding the stem between the Immunoglobulin domains and the transmembrane region. KIR3DL3 gene is not a pseudogene but encodes a protein that is not expressed in healthy individuals. Protein expression might be induced under certain developmental or pathological situations. |
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Please read the User Guide of Recombinant Proteins for more specific information.
KIR3DL3 Protein, Human, Recombinant (His) KIR44 KIR3DL7 KIR-44 CD158Z KIRC1 KIR 44 killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 3 KIR2DS2 KIRC-1 KIRC 1 recombinant recombinant-proteins proteins protein