LILRB3/CD85a Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is AAI04994.1.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 在庫あり | ¥ 88,500 |
200 μg | 約5 days | ¥ 156,500 |
500 μg | 約5 days | ¥ 330,500 |
生物学的情報 | Testing in progress |
説明 | LILRB3/CD85a Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 72.9 kDa and the accession number is AAI04994.1. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-hFc |
Accession Number | AAI04994.1 |
別名 | LILRA6, CD85A, ILT-5, LIR-3, leukocyte immunoglobulin like receptor B3, MGC138403, PIRB, LIR3, ILT5, XXbac-BCX105G6.7, HL9 |
Construction | The Human LILRB3 (AAI04994.1) (Met1-Glu443) was expressed with the Fc region of Human IgG1 at the C-terminus. |
Protein Purity |
> 95 % as determined by SDS-PAGE.
|
分子量 | 72.9 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Leukocyte immunoglobulin-like receptor subfamily B member 3, also known as Leukocyte immunoglobulin-like receptor 3, Immunoglobulin-like transcript 5, Monocyte inhibitory receptor HL9, CD85 antigen-like family member A, CD85a and LILRB3, is a single-pass type I membrane protein that belongs to the leukocyte receptor cluster (LRC) present on 19q13.4. LILRB3 / CD85a contains four Ig-like C2-type (immunoglobulin-like) domains. LILRB3 / CD85a contains three copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in the modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases. LILRB3 / CD85a is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found. |
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Please read the User Guide of Recombinant Proteins for more specific information.
LILRB3/CD85a Protein, Human, Recombinant (hFc) HL-9 LILRA6 LILRA-6 CD85A MGC 138403 ILT-5 LIR-3 MGC-138403 LIR 3 leukocyte immunoglobulin like receptor B3 MGC138403 PIRB LIR3 ILT5 ILT 5 XXbac-BCX105G6.7 LILRA 6 HL9 HL 9 recombinant recombinant-proteins proteins protein