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M-CSF/CSF1 Protein, Human, Recombinant (His)

カタログ番号 TMPJ-00327
別名: Lanimostim, M-CSF, CSF-1, MCSF, CSF1, Macrophage Colony-Stimulating Factor 1

Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
M-CSF/CSF1 Protein, Human, Recombinant (His)
パッケージサイズ 在庫状況 単価(税別)
10 μg 在庫あり ¥ 27,000
50 μg 約5 days ¥ 80,500
500 μg 約5 days ¥ 525,500
1 mg 約5 days ¥ 750,500
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生物学的特性に関する説明
Technical Params
Product Properties
生物学的情報 Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. The ED50 for this effect is 4.16 ng/ml. (Regularly tested)

説明 Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.
Species Human
Expression Host HEK293 Cells
Tag C-6xHis
Accession Number P09603
別名 Lanimostim, M-CSF, CSF-1, MCSF, CSF1, Macrophage Colony-Stimulating Factor 1
Amino Acid Glu33-Arg255
Construction Glu33-Arg255
Protein Purity Greater than 95% as determined by reducing SDS-PAGE. (QC verified)

分子量 41 KDa (reducing condition)
Endotoxin < 0.001 ng/µg (0.01 EU/µg) as determined by LAL test.
Formulation Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, pH 7.2.
Reconstitution Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
Stability & Storage

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

Research Background Macrophage Colony-Stimulating Factors (m-csf) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and themonocytes-macrophages. CSF-1 promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. CSF-1 is required for normal male and female fertility and promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. it also plays a role in lipoprotein clearance.

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技術サポート

Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

M-CSF/CSF1 Protein, Human, Recombinant (His) Lanimostim M-CSF CSF-1 CSF 1 MCSF CSF1 Macrophage Colony-Stimulating Factor 1 recombinant recombinant-proteins proteins protein