MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 144,000 |
500 μg | 約5 days | ¥ 576,000 |
1 mg | 約5 days | ¥ 964,000 |
説明 | MASP2 Protein, Cynomolgus, Recombinant (His) is expressed in E. coli expression system with C-His tag. The predicted molecular weight is 46.8 kDa and the accession number is A0A2K5UJY0. |
Species | Cynomolgus |
Expression Host | E. coli |
Tag | C-His |
Accession Number | A0A2K5UJY0 |
別名 | MAP19, MASP1P1, MASP-2, sMap |
Construction | Thr287-Phe686 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
分子量 | 46.8 kDa (predicted). Due to autocatalytic cleavage, the protein migrates to 21-24 kDa&28-30 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM Tris, 200 mM NaCl (pH 9.0). Typically, 8% trehalose is incorporated as a protective agent before lyophilization. |
Reconstitution | Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | The dysregulation of complement cascade leads to unsolicited cytokine storm, inflammation, deterioration of alveolar lining cells, culminating in acquired respiratory destructive syndrome (ARDS). Similar pathogenesis is observed with the middle east respiratory syndrome (MERS), severe acquired respiratory syndrome (SARS), and SARS-CoV-2. Activation of the lectin pathway via mannose-binding lectin associated serine protease 2 (MASP2) is witnessed under discrete viral infections including COVID-19. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
MASP2 Protein, Cynomolgus, Recombinant (His) MAP 19 MASP 2 MAP19 MASP1P1 MASP-2 sMap MASP2 MAP-19 recombinant recombinant-proteins proteins protein