MIP-5 Protein, Human, Recombinant (aa 22-113, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 11.7 kDa and the accession number is Q16663-1.
説明 | MIP-5 Protein, Human, Recombinant (aa 22-113, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 11.7 kDa and the accession number is Q16663-1. |
Species | Human |
Expression Host | E. coli |
Tag | His |
Accession Number | Q16663-1 |
別名 | LKN-1, MIP-5, SY15, MIP-1 δ, MIP-1D, HMRP-2B, HCC-2, NCC-3, chemokine (C-C motif) ligand 15, MIP-1 delta, SCYA15, LKN1, NCC3, SCYL3, MRP-2B |
Construction | A DNA sequence encoding the mature form of human CCL15 (Q16663-1) (Gln 22-Ile 113) was expressed, with a polyhistide tag at the C-terminus. |
Protein Purity | > 95 % as determined by SDS-PAGE |
分子量 | 11.7 kDa (predicted) |
Endotoxin | Please contact us for more information. |
Formulation | Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0. 01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA. |
Reconstitution | A hardcopy of datasheet with reconstitution instructions is sent along with the products. Please refer to it for detailed information. |
Stability & Storage |
Samples are stable for up to twelve months from date of receipt at -20℃ to -80℃. Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Shipping |
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. |
Research Background | Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokine ligand 15 (CCL15), also known as leukotactin-1, MIP5, MIP1 and HCC-2, is a small cytokine belonging to the C-C chemokine family. CCL15 is prevantly expressed in liver, small intestine, colon, and in certain leukocytes and macrophages of the lung. It is chemotactic for neutrophils, monocytes, and lymphocytes and elicits its effects by binding to cell surface chemokine receptors like CCR1 and CCR3. |
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Please read the User Guide of Recombinant Proteins for more specific information.
MIP-5 Protein, Human, Recombinant (aa 22-113, His) MIP 5 LKN-1 MIP-5 SY15 MIP-1 δ MIP-1D MIP5 HMRP-2B HCC-2 LKN 1 SCYL-3 NCC 3 NCC-3 SCYA-15 HCC 2 SY 15 chemokine (C-C motif) ligand 15 MIP-1 delta SCYA15 SCYA 15 SCYL 3 LKN1 SY-15 NCC3 HCC2 SCYL3 MRP-2B recombinant recombinant-proteins proteins protein