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MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)

カタログ番号 TMPY-04365
別名: SAPKK3, mitogen-activated protein kinase kinase 6, MKK6, MAPKK6, MEK6, PRKMK6, SAPKK-3

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.
MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST)
パッケージサイズ 在庫状況 単価(税別)
50 μg 約5 days ¥ 114,500
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生物学的特性に関する説明
Technical Params
Product Properties
参考文献
説明 MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 65.3 kDa and the accession number is P52564-1.
Species Human
Expression Host Baculovirus Insect Cells
Tag His, GST
Accession Number P52564-1
別名 SAPKK3, mitogen-activated protein kinase kinase 6, MKK6, MAPKK6, MEK6, PRKMK6, SAPKK-3
Construction The Human MAP2K6 isoform 1 (P52564-1) (Met 1-Asp 334, Ser 207/Asp, Thr 211/Asp) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
Protein Purity > 88 % as determined by SDS-PAGE
分子量 65.3 kDa (predicted)
Endotoxin < 1.0 EU/μg of the protein as determined by the LAL method.
Formulation Supplied as sterile 20 mM Tris, 500 mM NaCl, pH 8.0, 10% glycerol.
Reconstitution A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information.
Stability & Storage

It is recommended to store the product under sterile conditions at -20℃ to -80℃. Samples are stable for up to 12 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

Shipping

Kinases are highly recommended to be shipped at frozen temperature with blue ice or dry ice.

Research Background Dual specificity mitogen-activated protein kinase kinase 6, also known as MAP kinase kinase 6, MAPKK 6, MAPK / ERK kinase 6, SAPKK3, MAP2K6, and MKK6, is a protein that belongs to the protein kinase superfamily, STE Ser / Thr protein kinase family and MAP kinase kinase subfamily. MAP2K6 / MKK6 contains one protein kinase domain. Mitogen-activated protein kinases are members of a conserved cascade of kinases involved in many signal transduction pathways. They stimulate phosphorylation of transcription factors in response to extracellular signals such as growth factors, cytokines, ultraviolet light, and stress-inducing agents. MAP2K6 / MKK6 exists in a variety of alternatively spliced isoforms with distinct patterns of tissue expression. Isoform 2 of MAP2K6 / MKK6 is only expressed in skeletal muscle. Isoform 1 of MAP2K6 / MKK6 is expressed in skeletal muscle, heart, and to a lesser extent in liver or pancreas.

参考文献

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Please read the User Guide of Recombinant Proteins for more specific information.

Keywords

MKK6 Protein, Human, Recombinant (S207D, T211D, His & GST) SAPKK3 MEK 6 mitogen-activated protein kinase kinase 6 MKK6 PRKMK-6 PRKMK 6 MAPKK6 MKK 6 MAPKK 6 MAPKK-6 MEK6 MKK-6 PRKMK6 SAPKK-3 SAPKK 3 MEK-6 recombinant recombinant-proteins proteins protein