MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled

MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.2 kDa and the accession number is Q13421-2.

MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled

パッケージサイズ	在庫状況	単価(税別)
100 μg	約5 days	￥ 321,500
500 μg	約5 days	￥ 854,000
1 mg	約5 days	￥ 1,425,500

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説明	MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 35.2 kDa and the accession number is Q13421-2.

Species	Human
Expression Host	HEK293
Tag	C-His-Avi
Accession Number	Q13421-2
別名	MSLN, MPF, CAK1, Mesothelin, MPFSMRP, SMR
Construction	Recombinant FITC-Labeled Human MSLN/Mesothelin Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus. It contains Glu296-Gly580.[Accession \|Q13421-2]
Protein Purity	> 95% as determined by Tris-Bis PAGE
分子量	The protein has a predicted MW of 35.2 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

Endotoxin	Less than 1EU per μg by the LAL method.
Formulation	Supplied as 0.22μm filtered solution in PBS (pH 7.4).
Stability & Storage	Valid for 12 months from date of receipt when stored at -80°C. Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Research Background	Mesothelin, also known as MSLN, is a protein that in humans is encoded by the MSLN gene.Cloning studies showed that the mesothelin gene encodes a precursor protein that is processed to yield mesothelin which is attached to the cell membrane by a glycophosphatidylinositol linkage and a 31-kDa shed fragment named megakaryocyte-potentiating factor (MPF). Although it has been proposed that mesothelin may be involved in cell adhesion, its biological function is not known.A knockout mouse line that lacks mesothelin reproduces and develops normally.

参考文献

1. Adusumilli P S, et al. Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity[J]. Science Translational Medicine, 2014, 6(261):261ra151-261ra15

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MSLN/Mesothelin Protein, Human, Recombinant (His & Avi), FITC-Labeled

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