Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
10 μg | 約5 days | ¥ 42,500 |
50 μg | 約5 days | ¥ 125,000 |
500 μg | 約5 days | ¥ 475,000 |
1 mg | 約5 days | ¥ 682,000 |
説明 | Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide. |
Species | Human |
Expression Host | E. coli |
Tag | Tag Free |
Accession Number | O60760 |
別名 | Glutathione-Requiring Prostaglandin D Synthase, PGDS, Glutathione S-Transferase, PTGDS2, GST Class-Sigma, H-PGDS, GSTS, Prostaglandin-H2 D-Isomerase, Hematopoietic Prostaglandin D Synthase, HPGDS, GST Class-σ, Glutathione-Dependent PGD Synthase |
Amino Acid | Met1-Leu199 |
Construction | Met1-Leu199 |
Protein Purity | Greater than 95% as determined by reducing SDS-PAGE. (QC verified) |
分子量 | 26 KDa (reducing condition) |
Endotoxin | < 0.1 ng/µg (1 EU/µg) as determined by LAL test. |
Formulation | Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 200 mM NaCl, pH 7.0. |
Stability & Storage |
Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
PGDS Protein, Human, Recombinant Glutathione-Requiring Prostaglandin D Synthase PTGDS-2 PGDS Glutathione S-Transferase PTGDS2 GST Class-Sigma H-PGDS GSTS Prostaglandin-H2 D-Isomerase Hematopoietic Prostaglandin D Synthase HPGDS PTGDS 2 GST Class-σ Glutathione-Dependent PGD Synthase recombinant recombinant-proteins proteins protein