Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. PGLYRP1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is O88593.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 約5 days | ¥ 107,000 |
500 μg | 約5 days | ¥ 424,500 |
1 mg | 約5 days | ¥ 711,500 |
説明 | Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. PGLYRP1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.7 kDa and the accession number is O88593. |
Species | Mouse |
Expression Host | HEK293 Cells |
Tag | C-hFc |
Accession Number | O88593 |
別名 | PGRPSMGC126896, TNFSF3L, PGLYRP1, TAG7, PGLYRP, PGRP, PGRP-SMGC126894, PGRP-S, Tasg7 |
Construction | Phe19-Glu182 |
Protein Purity | > 95% as determined by Tris-Bis PAGE |
分子量 | 45.7 kDa (predicted). Due to glycosylation, the protein migrates to 50-55 kDa based on Tris-Bis PAGE result. |
Endotoxin | < 1 EU/μg by the LAL method. |
Formulation | Supplied as 0.22 μm filtered solution in PBS, 10% Glycerol (pH 8.0). |
Stability & Storage |
It is recommended to store the product under sterile conditions at -70℃ or lower. Samples are stable for up to 12 months at -80℃. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. |
Research Background | Innate immunity protein Tag7 (PGRP-S, PGLYRP1) can interact with the TNFα receptor, TNFR1, and block the transduction of apoptotic signals through this receptor. A complex formed between the Tag7 protein and the major heat shock protein Hsp70 can activate TNFR1 receptor and induce tumor cell death via either apoptotic or necroptotic pathway. |
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Please read the User Guide of Recombinant Proteins for more specific information.
PGLYRP1 Protein, Mouse, Recombinant (hFc) PGRPSMGC 126896 PGLYRP 1 PGRP-SMGC 126894 PGRPSMGC126896 TNFSF3L PGLYRP1 PGRPSMGC-126896 PGRP-SMGC-126894 TAG-7 PGLYRP-1 TAG7 PGLYRP PGRP PGRP-SMGC126894 PGRP-S TAG 7 Tasg7 recombinant recombinant-proteins proteins protein