Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
100 μg | 在庫あり | ¥ 103,500 |
200 μg | 約5 days | ¥ 177,000 |
500 μg | 約5 days | ¥ 358,000 |
生物学的情報 | Testing in progress |
説明 | Prostaglandin D2 Synthase Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.1 kDa and the accession number is P41222. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | C-His |
Accession Number | P41222 |
別名 | PDS, L-PGDS, PGDS, PGDS2, LPGDS, PGD2, prostaglandin D2 synthase 21kDa (brain) |
Construction | The Human PTGDS (P41222) (Met1-Gln190) was expressed with a polyhistidine tag at the C-terminus. |
Protein Purity |
≥ 80 % as determined by SDS-PAGE. ≥ 90 % as determined by SEC-HPLC.
|
分子量 | 20.1 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | PTGDS, also known as L-PGDS, belongs to the calycin superfamily, lipocalin family. Lipocalins share limited regions of sequence homology and a common tertiary structure architecture. They transport small hydrophobic molecules such as steroids, bilins, retinoids, and lipids. PTGDS is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of PGH2 to PGD2. It is involved in smooth muscle contraction/relaxation and a variety of central nervous system functions. PTGDS may have an anti-apoptotic role in oligodendrocytes. It binds small non-substrate lipophilic molecules, including biliverdin, bilirubin, retinal, retinoic acid and thyroid hormone, and may act as a scavenger for harmful hydrophopic molecules and as a secretory retinoid and thyroid hormone transporter. It is likely to play important roles in both maturation and maintenance of the central nervous system and male reproductive system. |
bottom
Please read the User Guide of Recombinant Proteins for more specific information.
Prostaglandin D2 Synthase Protein, Human, Recombinant (His) PGD-2 PGD 2 PDS brain PGDS 2 L-PGDS prostaglandin D2 synthase 21kDa PGDS PGDS2 LPGDS PGD2 prostaglandin D2 synthase 21kDa (brain) PGDS-2 recombinant recombinant-proteins proteins protein