PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1.
パッケージサイズ | 在庫状況 | 単価(税別) |
---|---|---|
50 μg | 在庫あり | ¥ 57,500 |
100 μg | 約5 days | ¥ 98,500 |
200 μg | 約5 days | ¥ 167,000 |
500 μg | 約5 days | ¥ 523,500 |
生物学的情報 | Measured by its ability to hydrolyze the substrate N-acetyl-L-Asp-L-Glu into N-acetyl-L-Asp and L-Glu. The L-Glu product is measured by fluorescence after its derivatization by ortho-phthaldialdehyde. The specific activity is >400 pmol/min/µg, as measured under the described conditions. |
説明 | PSMA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 81.86 kDa and the accession number is Q04609-1. |
Species | Human |
Expression Host | HEK293 Cells |
Tag | N-His |
Accession Number | Q04609-1 |
別名 | FGCP, GCP2, PSMA, GCPII, NAALAdase, folate hydrolase (prostate-specific membrane antigen) 1, FOLH, PSM, mGCP, NAALAD1 |
Construction | Human FOLH1 (NP_004467.1) (Lys44-Ala750) |
Protein Purity |
> 95 % as determined by SDS-PAGE.
|
分子量 | 81.86 kDa (predicted) |
Endotoxin | < 1.0 EU/μg of the protein as determined by the LAL method. |
Formulation | Lyophilized from a solution filtered through a 0.22 μm filter, containing 0.9 mM CaCl2, 0.5 mM MgCl2-6H2O, 2. 7 mM KCl, 1. 5 mM KH2PO4, 137.9 mM NaCl, 8.1 mM Na2HPO4-7H2O, 0.5 mM ZnCl2, pH 7.2. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
Reconstitution | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
Stability & Storage |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
Shipping |
In general, Lyophilized powders are shipping with blue ice. |
Research Background | Glutamate carboxypeptidase 2, also known as Glutamate carboxypeptidase II, Membrane glutamate carboxypeptidase, Prostate-specific membrane antigen, GCPII, PSMA, FOLH1, and NAALAD1, is a single-pass type II membrane protein which belongs to thepeptidase M28 family and M28B subfamily. FOLH1 is highly expressed in prostate epithelium. It is detected in urinary bladder, kidney, testis, ovary, fallopian tube, breast, adrenal gland, liver, esophagus, stomach, small intestine, colon, brain (at protein level), and the capillary endothelium of a variety of tumors. FOLH1 has both folate hydrolase and N-acetylated alpha linked acidic dipeptidase (NAALADase) activity. It has a preference for tri-alpha-glutamate peptides. Genetic variation in FOLH1 may be associated with low folate levels and consequent hyperhomocysteinemia. This condition can result in increased risk of cardiovascular disease, neural tube defects, and cognitive deficits. FOLH1 also shows a promising role in directed imaging and therapy of recurrent or metastatic disease.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
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Please read the User Guide of Recombinant Proteins for more specific information.
PSMA Protein, Human, Recombinant (His) FGCP GCP2 GCP-2 NAALAD-1 PSMA GCPII GCP 2 NAALAD 1 NAALAdase folate hydrolase (prostate-specific membrane antigen) 1 FOLH PSM mGCP NAALAD1 recombinant recombinant-proteins proteins protein